Medicines Models

These models and simulations have been tagged “Medicines”.

This model shows the Pharmaceutical New Drug Pipeline based on drug release, approval and patent expiry. This pipeline is then linked to patients switching from older drugs to newer drugs based on proven indications and marketing (indication creep). Based on work by Mark Heffernan on the Australian
Supply Overuse Medicines Health Care Waste

This model shows the Pharmaceutical New Drug Pipeline based on drug release, approval and patent expiry. This pipeline is then linked to patients switching from older drugs to newer drugs based on proven indications and marketing (indication creep). Based on work by Mark Heffernan on the Australian Pharmaceutical Benefits Scheme for drug subsidy.Conference paper and Larger ithink model

Pharmaceutical Pipeline and Medicines Use
Geoff McDonnell
Mental Health Platform Post-Covid June 2021 including revisiting Wiser Health Decisions
Psychiatry EHealth Technology Culture Capability Medicines Psychology Infection Decision Making Clinical Behavior Mental Health Platform
Mental Health Platform Post-Covid June 2021 including revisiting Wiser Health Decisions
Mental Health Platform
Geoff McDonnell
3
A simple error chain of medication errors for patients in hospital. Serious medication errors in inpatients with drug orders sometimes result in Adverse Drug Events (ADE) and Deaths. See next  IM-646
Clinical Care Safety Medicines Health Care

A simple error chain of medication errors for patients in hospital. Serious medication errors in inpatients with drug orders sometimes result in Adverse Drug Events (ADE) and Deaths. See next IM-646

Medication error inpatients 1
Geoff McDonnell
Causal loop diagram patient centric version of  Insight 691 , unfolding the complexity of medication management.
Supply Technology Medicines Health Care CLD

Causal loop diagram patient centric version of Insight 691, unfolding the complexity of medication management.

Medication Management CLD
Geoff McDonnell
Addition of Incident Reporting and Prevention Interventions to a simple error chain of medication errors for patients in hospital IM-10113  
Health Care Clinical Care Safety Medicines

Addition of Incident Reporting and Prevention Interventions to a simple error chain of medication errors for patients in hospital IM-10113 

Medication error with incident reporting
Geoff McDonnell
WIP ​Based on TAble 1 Jackson 2014  article
Treatment Health Care Behavior COM-B Medicines Adherence
WIP ​Based on TAble 1 Jackson 2014 article
Applying COM-B to medication adherence
Geoff McDonnell
3
From Nancy Leveson Vioxx Recall Study in CH8  Engineering a Safer World  and Couturier's MIT ESD Thesis
Medicines Health Care Performance Safety
From Nancy Leveson Vioxx Recall Study in CH8 Engineering a Safer World and Couturier's MIT ESD Thesis
Prescribing and Drug Recall Pressures
Geoff McDonnell
Major stocks and flows of Erythropoiesis and Erythropoiesis Stimulating Agents (ESA) Dosing in Anemia due to Renal Failure from Jim Rogers. See Simulation Insight
Kidney Medicines Renal Health Care Biomedical

Major stocks and flows of Erythropoiesis and Erythropoiesis Stimulating Agents (ESA) Dosing in Anemia due to Renal Failure from Jim Rogers. See Simulation Insight


ESA Dosing in Renal Anemia
Geoff McDonnell
From p592 Doyle F et al.(2007) Journal of Process Control 17 571-594 abstract
Health Care Control Biomedical Medicines

From p592 Doyle F et al.(2007) Journal of Process Control 17 571-594


abstract
Heparin Kinetics
Geoff McDonnell
Rich picture version of causal loop diagram for medication errors, showing the importance of reporting, analyzing and fixing knowledge and process errors. Medication errors will tend to grow due to the use of more medications in more complex patients. This is exacerbated by the loss of staff knowled
Medicines Safety Informatics Performance Health Care Clinical Care
Rich picture version of causal loop diagram for medication errors, showing the importance of reporting, analyzing and fixing knowledge and process errors. Medication errors will tend to grow due to the use of more medications in more complex patients. This is exacerbated by the loss of staff knowledge by turnover and goal erosion in places with harmful errors.
Medication error CLD
Geoff McDonnell
Rich picture version of causal loop diagram for medication errors, showing the importance of reporting, analyzing and fixing knowledge and process errors. Medication errors will tend to grow due to the use of more medications in more complex patients. This is exacerbated by the loss of staff knowled
Informatics Clinical Care Medicines Health Care Safety
Rich picture version of causal loop diagram for medication errors, showing the importance of reporting, analyzing and fixing knowledge and process errors. Medication errors will tend to grow due to the use of more medications in more complex patients. This is exacerbated by the loss of staff knowledge by turnover and goal erosion in places with harmful errors.
Clone of Medication error CLD
hltay
The dynamics of methadone treatment for intravenous opioid users. The major flows in this study were people cycling between being on methadone and off treatment. This is a minimal model of the insights from the more detailed modelling project described in   Monograph pdf
Methadone Drug Opioid Health Care Policy Medicines

The dynamics of methadone treatment for intravenous opioid users. The major flows in this study were people cycling between being on methadone and off treatment. This is a minimal model of the insights from the more detailed modelling project described in  Monograph pdf

Methadone Treatment Dynamics
Geoff McDonnell
Rich picture version of causal loop diagram for medication errors, showing the importance of reporting, analyzing and fixing knowledge and process errors. Medication errors will tend to grow due to the use of more medications in more complex patients. This is exacerbated by the loss of staff knowle
Informatics Safety Clinical Care Medicines Health Care

Rich picture version of causal loop diagram for medication errors, showing the importance of reporting, analyzing and fixing knowledge and process errors. Medication errors will tend to grow due to the use of more medications in more complex patients. This is exacerbated by the loss of staff knowledge by turnover and goal erosion in places with harmful errors.

Clone of Medication error CLD
AGG
WIP ​Based on TAble 1 Jackson 2014  article
Treatment Health Care Behavior COM-B Medicines Adherence
WIP ​Based on TAble 1 Jackson 2014 article
Clone of Applying COM-B to medication adherence
L Kurt Kreuger
WIP Summary of Levin Roberts and Hirsch 1975 book subtitled A Computer-Aided Search for Heroin Policy using System Dynamics
Drug Policy Health Care Opioid Addiction Medicines
WIP Summary of Levin Roberts and Hirsch 1975 book subtitled A Computer-Aided Search for Heroin Policy using System Dynamics
The Persistent Poppy
Geoff McDonnell
Mind map example of a medication management project. See also  IM-692  for CLD
Health Care Medicines Technology Supply

Mind map example of a medication management project.

See also IM-692 for CLD

Medication Management Map
Geoff McDonnell
Mind map example of a medication management project. See also  IM-692  for CLD
Medicines Health Care Technology Supply

Mind map example of a medication management project.

See also IM-692 for CLD

Clone of Medication Management Map
Bob Donley
Explanation of delays in treatment effect and rebound effects on cessation of anti-depressant SSRI drugs based on Andrews
Depression Regulation Receptor Protein Biomedical Mental Health Medicines The Body And Self
Explanation of delays in treatment effect and rebound effects on cessation of anti-depressant SSRI drugs based on Andrews
Anti-depressants and oppositional perturbation
Geoff McDonnell