The dynamics of methadone treatment for intravenous opioid users. The major flows in this study were people cycling between being on methadone and off treatment. This is a minimal model of the insights from the more detailed modelling project described in Chalmers J, Ritter A, Heffernan M, McDonnell G. Modelling pharmacotherapy maintenance in Australia. A report prepared for the Australian National Council on Drugs. Sydney: Drug Policy Modelling Program, University of New South Wales; 2009 

Addition of Incident Reporting and Prevention Interventions to a simple error chain of medication errors for patients in hospital IM-10113 

This model shows the Pharmaceutical New Drug Pipeline based on drug release, approval and patent expiry. This pipeline is then linked to patients switching from older drugs to newer drugs based on proven indications and marketing (indication creep). Based on work by Mark Heffernan on the Australian Pharmaceutical Benefits Scheme for drug subsidy.Conference paper and Larger ithink model

Mind map example of a medication management project.

See also IM-692 for CLD

WIP ​Based on TAble 1 Jackson 2014 article

Mental Health Platform Post-Covid June 2021 including revisiting Wiser Health Decisions

Rich picture version of causal loop diagram for medication errors, showing the importance of reporting, analyzing and fixing knowledge and process errors. Medication errors will tend to grow due to the use of more medications in more complex patients. This is exacerbated by the loss of staff knowledge by turnover and goal erosion in places with harmful errors.

Explanation of delays in treatment effect and rebound effects on cessation of anti-depressant SSRI drugs based on Andrews

From p592 Doyle F et al.(2007) Journal of Process Control 17 571-594

abstract

Rich picture version of causal loop diagram for medication errors, showing the importance of reporting, analyzing and fixing knowledge and process errors. Medication errors will tend to grow due to the use of more medications in more complex patients. This is exacerbated by the loss of staff knowledge by turnover and goal erosion in places with harmful errors.

A simple error chain of medication errors for patients in hospital. Serious medication errors in inpatients with drug orders sometimes result in Adverse Drug Events (ADE) and Deaths. See next IM-646

Rich picture version of causal loop diagram for medication errors, showing the importance of reporting, analyzing and fixing knowledge and process errors. Medication errors will tend to grow due to the use of more medications in more complex patients. This is exacerbated by the loss of staff knowledge by turnover and goal erosion in places with harmful errors.

Major stocks and flows of Erythropoiesis and Erythropoiesis Stimulating Agents (ESA) Dosing in Anemia due to Renal Failure from Jim Rogers. See Simulation Insight

Causal loop diagram patient centric version of Insight 691, unfolding the complexity of medication management.

WIP Summary of Levin Roberts and Hirsch 1975 book subtitled A Computer-Aided Search for Heroin Policy using System Dynamics

From Nancy Leveson Vioxx Recall Study in CH8 Engineering a Safer World and Couturier's MIT ESD Thesis

WIP ​Based on TAble 1 Jackson 2014 article

Mind map example of a medication management project.

See also IM-692 for CLD

WIP based on Lecture 4 and 11 of Uri Alon's 2024-5 course on Systems Aging repeated in 2025-6 System biology of aging and longevity 

WIP based on Lecture 10 and 11 of Uri Alon's 2024-5 course on Systems Aging repeated in 2025-6 System biology of aging and longevity