Physiology Models

These models and simulations have been tagged “Physiology”.

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guytonian model of the circulation
circ3
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WIP From  zenker 2007 article PLoS Computational Biology From Inverse Problems in Mathematical Physiology to Quantitative Differential Diagnoses
Cardiovascular Model
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WIP From  zenker 2007 article PLoS Computational Biology From Inverse Problems in Mathematical Physiology to Quantitative Differential Diagnoses
Clone of Cardiovascular Model
Insight diagram
WIP From  zenker 2007 article PLoS Computational Biology From Inverse Problems in Mathematical Physiology to Quantitative Differential Diagnoses
Clone of Cardiovascular Model
Insight diagram
Physiology based insight to compare the energy balance and carbohydrate insulin models described in Nature Metabolism Obesity Causal Model Differences 2024 article See also Speakman and Hall's 2021 science article and insight and Stock flow Comparisons insight
Physiological regulation of energy metabolism
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Simple dynamic modelling of body water + Na + urinary water and Na excretion - for teaching about tonicity, osmolarity and mean systemic filling pressure
Fluids and Electrolytes
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Minimal model of glucose kinetics insight as a physiology circuit  and the more general secrete and grow notif from Uri Alon's System Medicine added. The circuits are then expressed in System Dynamics maps which distinguish between links and flows and add both where required

System Medicine Physiological Circuits Glucose Secrete and Grow
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Weight Loss Physiology
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Periodic table of disease patterns and physiological circuits   from Ch 9 of Uri Alon's System Medicine Book Circuit motifs are modified to facilitate building system dynamics simulations

System Medicine Physiological Circuits Disease Patterns
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WIP Extension of the simplified Glucose minimal model (IM) as described in Ch 2 of Uri Alon's System Medicine Book  Values from Mohammed 2019 article. Copied from Mark Heffernan's Stella model (to be hosted)
BIG Beta cell Insulin Glucose Model
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Causal loop diagram of Eric Topol's substack post The Flawed V02 Max Craze: Conflation with Cardiorespiratory Fitness, based on my Gemini interaction using Gene Bellinger's AI prompts
The vO2 Max Aerobic capacity craze
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WIP From  zenker 2007 article PLoS Computational Biology From Inverse Problems in Mathematical Physiology to Quantitative Differential Diagnoses
Clone of Cardiovascular Model
4 weeks ago
Insight diagram
WIP From  zenker 2007 article PLoS Computational Biology From Inverse Problems in Mathematical Physiology to Quantitative Differential Diagnoses
Clone of Cardiovascular Model
3 weeks ago
Insight diagram
See also aging and wisdom insight
Sleep Alzheimer's and Brain Health