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This insight began as a March 22nd Clone of "Italian COVID 19 outbreak control"; thanks to Gabo HN for the original insight. The following links are theirs:

Initial data from:
Italian data [link] (Mar 4)
Incubation estimation [link]

Andy Long
Northern Kentucky University
May 2nd, 2020

This is an update of our model from April 9th, 2020. As we prepare for our final exam, I read a story in The Guardian about Italy's struggle to return to normalcy. The final paragraphs:

During the debate in the Senate on Thursday, the opposition parties grilled Conte. Ex-prime minister Matteo Renzi, who has called for less restraint in the reopening, remarked, “The people in Bergamo and Brescia who are gone, those who died of the virus, if they could speak, they’d tell us to relaunch the country for them, in their honour.”

Renzi’s controversial statement was harshly criticised by doctors who warned that the spread of the disease, which, as of Thursday, had killed almost 30,000 people in the country and infected more than 205,000 [ael: my emphasis], was not over and that a misstep could take the entire country back to mid-March coronavirus levels.

“We risk a new wave of infections and outbreaks if we’re not careful,” said Tullio Prestileo, an infectious diseases specialist at Palermo’s Benefratelli Hospital. “If we don’t realise this, we could easily find ourselves back where we started. In that case, we may not have the strength to get back up again.”

I have since updated the dataset, to include total cases from February 24th to May 2nd. I went to Harvard's Covid-19 website for Italy  and and then to their daily updates, available at github. I downloaded the regional csv file for May 2nd,  which had regional totals (21 regions); I grabbed the column "totale_casi" and did some processing to get the daily totals from the 24th of February to the 2nd of May.

The cases I obtained in this way matched those used by Gabo HN.

The initial data they used started on March 3rd (that's the 0 point in this Insight).

You can get a good fit to the data through April 9th by choosing the following (and notice that I've short-circuited the process from the Infectious to the Dead and Recovered). I've also added the Infectious to the Total cases.

The question is: how well did we do at modeling this epidemic through May 2nd (day 60)? And how can we change the model to do a better job of capturing the outbreak from March 3rd until May 2nd?

Incubation Rate:  .025
R0: 3
First Lockdown: IfThenElse(Days() == 5, 16000000, 0)
Total Lockdown: IfThenElse(Days() >= 7, 0.7,0)

(I didn't want to assume that the "Total Lockdown" wasn't leaky! So it gets successively tighter, but people are sloppy, so it simply goes to 0 exponentially, rather than completely all at once.)

deathrate: .01
recoveryrate: .03

"Death flow": [deathrate]*[Infectious]
"Recovery flow": [recoveryrate]*[Infectious]

Total Reported Cases: [Dead]+[Surviving / Survived]+[Infectious]

Based on my student Sean's work, I altered the death rate to introduce the notion that doctors are getting better at saving lives:
[deathrate] = 0.02/(.0022*Days()^1.8+1)
I don't agree with this model of the death rate, but it was a start motivated by his work. Thanks Sean!:)

Resources:
  * Recent news: "Since the early days of the outbreak in China, scientists have known that SARS-CoV-2 is unusually contagious — more so than influenza or a typical cold virus. Scientific estimates of the reproduction number — the R0, which is the number of new infections that each infected person generates on average — have varied among different communities and different points but have generally been between 2 and 4. That is significantly higher than seasonal influenza."
  * https://annals.org/aim/fullarticle/2762808/incubation-period-coronavirus-disease-2019-covid-19-from-publicly-reported
  * https://covid19.healthdata.org/italy
Key of Final Version of Italian COVID-19 outbreak
Insight diagram

The complex model reflects the COVID-19 outbreak in Burnie, Tasmania. The model explains how the COVID-19 outbreak will influence the government policies and economic impacts. The infected population will be based on how many susceptible, infected, and recovered individuals in Burnie. It influences the probability of infected population meeting with susceptible individuals.

The fatality rate will be influenced by the elderly population and pre-existing medical conditions. Even though individuals can recover from COVID-19 disease, some of them will have immunity loss and become part of the susceptible individuals, or they will be diagnosed with long term illnesses (mental and physical). Thus, these variables influence the number of confirmed cases in Burnie and the implementation of government policies.

The government policies depend on the confirmed COVID-19 cases. The government policies include business restrictions, lock down, vaccination and testing rate. These variables have negative impacts on the infection of COVID-19 disease. However, these policies have some negative effects on commercial industry and positive effects on e-commerce and medical industry. These businesses growth rate can influence the economic growth of Burnie with the economic

Most of the variables are adjustable with the slider provided below. They can be adjusted from 0 to 1, which illustrates the percentages associated with the specific variables. They can also be adjusted to three decimal points, i.e., from 0.1 to 0.001.


Assumptions

- The maximum population of Burnie is 20000.
- The maximum number of infected individuals is 100.
- Government policies are triggered when the COVID-19 cases reach 10 or above.
- The government policies include business restrictions, lock down, vaccination and testing rates only. Other policies are not being considered under this model.
- The vaccination policy implemented by the government is compulsory.
- The testing rate is set by the government. The slider should not be changed unless the testing rate is adjusted by the government.
- The fatality rate is influenced by the elderly population and pre-existing medical conditions only. Other factors are not being considered under this model.
- People who recovered from COVID-19 disease will definitely suffer form immunity loss or any other long term illnesses.
- Long term illnesses include mental illnesses and physical illnesses only. Other illnesses are not being considered under this model.
- Economic activities are provided with an assumption value of 1000.
- The higher the number of COVID-19 cases, the more negative impact they have on the economy of Burnie. 


Interesting Insights

A higher recovery rate can decrease the number of COVID-19 cases as well as the probability of infected population meeting with susceptible persons, but it takes longer for the economy to recover compared to a lower recovery rate. A higher recovery rate can generate a larger number of people diagnosed with long term illnesses.

Testing rate triggers multiple variables, such as government policies, positive cases, susceptible and infected individuals. A lower testing rate can decrease the COVID-19 confirmed cases, but it can increase the number of susceptible people. And a higher testing rate can trigger the implementation of government policies, thus decreasing the infection rate. As the testing rate has a strong correlation with the government policies, it can also influence the economy of Burnie. 

BMA708 COVID-19 Outbreak in Burnie, Tasmania
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Covid-19 pandemi
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Clone nyoba2 of SEIR COVID-19 New Kl. 1
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SARS-CoV-19 spread in different countries
- please adjust variables accordingly

Italy
  • elderly population (>65): 0.228
  • estimated undetected cases factor: 4-11
  • starting population size: 60 000 000
  • high blood pressure: 0.32 (gbe-bund)
  • heart disease: 0.04 (statista)
  • free intensive care units: 3 100

Germany
  • elderly population (>65): 0.195 (bpb)
  • estimated undetected cases factor: 2-3 (deutschlandfunk)
  • starting population size: 83 000 000
  • high blood pressure: 0.26 (gbe-bund)
  • heart disease: 0.2-0.28 (herzstiftung)
  • free intensive care units: 5 880

France
  • elderly population (>65): 0.183 (statista)
  • estimated undetected cases factor: 3-5
  • starting population size: 67 000 000
  • high blood pressure: 0.3 (fondation-recherche-cardio-vasculaire)
  • heart disease: 0.1-0.2 (oecd)
  • free intensive care units: 3 000

As you wish
  • numbers of encounters/day: 1 = quarantine, 2-3 = practicing social distancing, 4-6 = heavy social life, 7-9 = not caring at all // default 2
  • practicing preventive measures (ie. washing hands regularly, not touching your face etc.): 0.1 (nobody does anything) - 1 (very strictly) // default 0.8
  • government elucidation: 0.1 (very bad) - 1 (highly transparent and educating) // default 0.9
  • Immunity rate (due to lacking data): 0 (you can't get immune) - 1 (once you had it you'll never get it again) // default 0.4

Key
  • Healthy: People are not infected with SARS-CoV-19 but could still get it
  • Infected: People have been infected and developed the disease COVID-19
  • Recovered: People just have recovered from COVID-19 and can't get it again in this stage
  • Dead: People died because of COVID-19
  • Immune: People got immune and can't get the disease again
  • Critical recovery percentage: Chance of survival with no special medical treatment
SARS-CoV-19 model
Insight diagram
COVID-19 in Jakarta