WIP based on Uri Alon's 2024-5 course on Systems Aging repeated in 2025-6 System biology of aging and longevity comprising 12 chapters
Systems Aging
Modificacion con propositos didacticos del modelo:
Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker
Glucose Insulin Model Info:
Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.
Clone of Glucose-Insulin Model in Type 1 Diabetes
Modificacion con propositos didacticos del modelo:
Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker
Glucose Insulin Model Info:
Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.
modificacion 2
Modificacion con propositos didacticos del modelo:
Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker
Glucose Insulin Model Info:
Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.
modificacion 3.
Modificacion con propositos didacticos del modelo:
Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker
Glucose Insulin Model Info:
Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.
modificacion 1
Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker
Glucose Insulin Model Info:
Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.
Clone of Glucose-Insulin Model in Type 1 Diabetes
WIP based on Chapters of Uri Alon's 2024-5 course on Systems Aging repeated in 2025-6 System biology of aging and longevity
Systems Aging Detail 2
WIP based on Chapter 3 Age Related Diseases of Uri Alon's 2024-5 course on Systems Aging repeated in 2025-6 System biology of aging and longevity
Systems Aging Detail of Age related Diseases
WIP based on Lecture 10 and 11 of Uri Alon's 2024-5 course on Systems Aging repeated in 2025-6 System biology of aging and longevity
Systems Aging Senolytic Pills and the Saturable removal model
WIP based on Lecture 4 of Uri Alon's 2024-5 course on Systems Aging repeated in 2025-6 System biology of aging and longevity
Systems Aging Menopause
WIP From zenker 2007 article PLoS Computational Biology From Inverse Problems in Mathematical Physiology to Quantitative Differential Diagnoses
Clone of Cardiovascular Model
Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.
Glucose minimal model Cambio #2
Mechanisms of long covid based on Faghy 2026 article Current
status and future perspectives on the mechanistic and pathophysiological understanding
of long COVID and my gemini interaction using Gene Bellinger's AI prompts
Long Covid mechanisms
WIP From zenker 2007 article PLoS Computational Biology From Inverse Problems in Mathematical Physiology to Quantitative Differential Diagnoses
Clone of Cardiovascular Model
Hannon and Ruth Modeling Dynamic Biological Systems p67 adapted to Bond Graph Kinetic Modeling Metabolic Map Alternate Layout of insight IM-857 Here Join and Split Flows are unfolded rather than using folders around the Stocks.
Author: (Michaelis Menten), version 2 with split and join
GRIPS25_06 Catalyzed Reaction
Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.
Glucose minimal model Cambio #2
Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.
Clone of Glucose minimal model
WIP based on Lecture 4 and 11 of Uri Alon's 2024-5 course on Systems Aging repeated in 2025-6 System biology of aging and longevity
Systems Aging Longevity genes and evolution
Causal loop summary of Belluz and Hall's 2025 Book, combined with Macronutrient metabolism and key biochemical metabolic cycles web article, based on my gemini interaction using Gene Bellinger's AI prompts
Food intelligence book summary
WIP based on Chapter 1 Universal patterns of ageing and Chapter 2 town garbage analogy of Uri Alon's 2024-5 course on Systems Aging repeated in 2025-6 System biology of aging and longevity
Systems Aging Ch1 Patterns and Ch2 Metaphor
Bond Graph Kinetic Modeling Metabolic Map by J LeFevre http://www.systemdynamics.org/conferences/2004/SDS_2004/PAPERS/379LEFEV.pdf
See also IM-857 and IM-2235 for more detail
Clone of Michaelis Menten Enzyme Metabolic Map
