Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hep

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

This three loop goal-seeking structure identifies the three key influences on managing blood glucose for people with diabetes - insulin injections reduce blood glucose levels, exercise reduces blood glucose levels, and food increases blood glucose levels.  The balance of all three is necessary to ma
This three loop goal-seeking structure identifies the three key influences on managing blood glucose for people with diabetes - insulin injections reduce blood glucose levels, exercise reduces blood glucose levels, and food increases blood glucose levels.  The balance of all three is necessary to manage diabetes.
 Addition of glucagon hormone action to control glucose homeostasis extended from  IM-586

Addition of glucagon hormone action to control glucose homeostasis extended from IM-586

 Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker     Glucose Insulin Model Info:  Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Spr

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker


Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

 Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

 A simple glucose regulation causal loop diagram taken from Richard O. Foster, 1970: The Dynamics of blood sugar regulation, MSc thesis, MIT Dept of Electrical Engineering, available on the MIT System Dynamics Group Literature Collection and in the MIT Electronic Libraries. See  IM-587  for Addition

A simple glucose regulation causal loop diagram taken from Richard O. Foster, 1970: The Dynamics of blood sugar regulation, MSc thesis, MIT Dept of Electrical Engineering, available on the MIT System Dynamics Group Literature Collection and in the MIT Electronic Libraries. See IM-587 for Addition of Glucagon

WIP example of Services oriented multiscale computable narrative synthesis focussed on Coping carefully with diabetes
WIP example of Services oriented multiscale computable narrative synthesis focussed on Coping carefully with diabetes
 Jones AP, Homer JB, Murphy DL, Essien JDK, Milstein B, Seville DA.  
 Understanding diabetes population dynamics through simulation modeling  
 and experimentation. American Journal of Public Health 2006;96(3):488-494. 
  http://ajph.aphapublications.org/cgi/content/abstract/96/3/488

Jones AP, Homer JB, Murphy DL, Essien JDK, Milstein B, Seville DA.

Understanding diabetes population dynamics through simulation modeling

and experimentation. American Journal of Public Health 2006;96(3):488-494.

http://ajph.aphapublications.org/cgi/content/abstract/96/3/488

 Addition of glucagon hormone action to control glucose homeostasis extended from  IM-586

Addition of glucagon hormone action to control glucose homeostasis extended from IM-586

Simple goal seeking loop for type 1 diabetes, describing relationship between blood glucose level, insulin injections, and food consumption, seeking to achieve healthy balanced blood glucose levels in the body.
Simple goal seeking loop for type 1 diabetes, describing relationship between blood glucose level, insulin injections, and food consumption, seeking to achieve healthy balanced blood glucose levels in the body.
This two loop goal-seeking structure identifies two factors to manage blood glucose for people with diabetes - insulin injections and exercise.
This two loop goal-seeking structure identifies two factors to manage blood glucose for people with diabetes - insulin injections and exercise.
 DIabetes incidence from population inflow, with undiagnosed and diagnosed stocks

DIabetes incidence from population inflow, with undiagnosed and diagnosed stocks

 Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker     Glucose Insulin Model Info:  Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Spr

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker


Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

 Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hep

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

 Sign graph model representing some of the dynamic relationships that exist in relation to diabetic patients and resulting impacted medical professions

Sign graph model representing some of the dynamic relationships that exist in relation to diabetic patients and resulting impacted medical professions

 DIabetes incidence inflow, Prevalence stock and deaths outflow

DIabetes incidence inflow, Prevalence stock and deaths outflow

 Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker     Glucose Insulin Model Info:  Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Spr

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker


Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

 Additional of glucagon hormone action to control glucose homeostasis

Additional of glucagon hormone action to control glucose homeostasis

 Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hep

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

 Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker     Glucose Insulin Model Info:  Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Spr

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker


Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.