Dosage per day, Doses per day, Every ? hours, Medicine in Intestines, Drug absorption, Plasma level, Blood volume, Plasma concentration, ​Toxic level, Medicinal level, Drug excretion, Excretion rate, Half-Life

Dosage per day, Doses per day, Every ? hours, Medicine in Intestines, Drug absorption, Plasma level, Blood volume, Plasma concentration, ​Toxic level, Medicinal level, Drug excretion, Excretion rate, Half-Life

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Dosage per day, Doses per day, Every ? hours, Medicine in Intestines, Drug absorption, Plasma level, Blood volume, Plasma concentration, ​Toxic level, Medicinal level, Drug excretion, Excretion rate, Half-Life

Dosage per day, Doses per day, Every ? hours, Medicine in Intestines, Drug absorption, Plasma level, Blood volume, Plasma concentration, ​Toxic level, Medicinal level, Drug excretion, Excretion rate, Half-Life

Dosage per day, Doses per day, Every ? hours, Medicine in Intestines, Drug absorption, Plasma level, Blood volume, Plasma concentration, ​Toxic level, Medicinal level, Drug excretion, Excretion rate, Half-Life

Dosage per day, Doses per day, Every ? hours, Medicine in Intestines, Drug absorption, Plasma level, Blood volume, Plasma concentration, ​Toxic level, Medicinal level, Drug excretion, Excretion rate, Half-Life

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker

Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Periodic table of disease patterns and physiological circuits   from Ch 9 of Uri Alon's System Medicine Book Cicuit motifs are modified to facilitate building system dynamics simulations

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

Dosage per day, Doses per day, Every ? hours, Medicine in Intestines, Drug absorption, Plasma level, Blood volume, Plasma concentration, ​Toxic level, Medicinal level, Drug excretion, Excretion rate, Half-Life

Dosage per day, Doses per day, Every ? hours, Medicine in Intestines, Drug absorption, Plasma level, Blood volume, Plasma concentration, ​Toxic level, Medicinal level, Drug excretion, Excretion rate, Half-Life

Tissue repair process of Inflammation with fibrosis or healing physiological circuits  from Ch 5 of Uri Alon's System Medicine Book

Part II of Immune System Dynamics showing the Phases of the Immune Response and some details of each phase

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Dosage per day, Doses per day, Every ? hours, Medicine in Intestines, Drug absorption, Plasma level, Blood volume, Plasma concentration, ​Toxic level, Medicinal level, Drug excretion, Excretion rate, Half-Life

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Hannon and Ruth Modeling Dynamic Biological Systems p67 adapted to Bond Graph Kinetic Modeling Metabolic Map Alternate Layout of insight IM-857 Here Join and Split Flows are unfolded rather than using folders around the Stocks.

A simple glucose regulation causal loop diagram taken from Richard O. Foster, 1970: The Dynamics of blood sugar regulation, MSc thesis, MIT Dept of Electrical Engineering, available on the MIT System Dynamics Group Literature Collection and in the MIT Electronic Libraries. See IM-587 for Addition of Glucagon

A simple glucose regulation causal loop diagram taken from Richard O. Foster, 1970: The Dynamics of blood sugar regulation, MSc thesis, MIT Dept of Electrical Engineering, available on the MIT System Dynamics Group Literature Collection and in the MIT Electronic Libraries. See IM-587 for Addition of Glucagon

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.