Insight diagram

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Clone of Glucose minimal model
Insight diagram

WIP Physiological circuits insight integrated with other articles on inflammation fibrosis and innate immunity

Multiscale integration of Inflammation and fibrosis
Insight diagram

Modificacion con propositos didacticos del modelo: 

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker


Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

modificacion 1
12 months ago
Insight diagram

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Clone of Glucose minimal model
Insight diagram

Modificacion con propositos didacticos del modelo: 

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker


Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

modificacion 3.
12 months ago
Insight diagram

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker


Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

Clone of Glucose-Insulin Model in Type 1 Diabetes
12 months ago
Insight diagram
Healht
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Insight diagram

Hannon and Ruth Modeling Dynamic Biological Systems p67 adapted to Bond Graph Kinetic Modeling Metabolic Map Alternate Layout of insight IM-857 Here Join and Split Flows are unfolded rather than using folders around the Stocks.

Author: (Michaelis Menten), version 2 with split and join

GRIPS25_06 Catalyzed Reaction
3 11 months ago
Insight diagram

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Glucose minimal model Cambio #2
Insight diagram
WIP From  zenker 2007 article PLoS Computational Biology From Inverse Problems in Mathematical Physiology to Quantitative Differential Diagnoses
Clone of Cardiovascular Model
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Insight diagram
WIP From  zenker 2007 article PLoS Computational Biology From Inverse Problems in Mathematical Physiology to Quantitative Differential Diagnoses
Clone of Cardiovascular Model
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Insight diagram
WIP based on Chapters of Uri Alon's 2024-5 course on Systems Aging repeated in 2025-6 System biology of aging and longevity 
Systems Aging Detail 2
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Insight diagram
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Insight diagram
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Insight diagram
WIP based on Lecture 4 of Uri Alon's 2024-5 course on Systems Aging repeated in 2025-6 System biology of aging and longevity 
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Insight diagram
WIP based on Lecture 4 and 11 of Uri Alon's 2024-5 course on Systems Aging repeated in 2025-6 System biology of aging and longevity 
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Insight diagram

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Clone of Glucose minimal model
Insight diagram
WIP based on Chapter 1 Universal patterns of ageing and Chapter 2 town garbage analogy of Uri Alon's 2024-5 course on Systems Aging repeated in 2025-6 System biology of aging and longevity 
Systems Aging Ch1 Patterns and Ch2 Metaphor
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Insight diagram
Causal loop summary of Belluz and Hall's 2025 Book, combined with Macronutrient metabolism and key biochemical metabolic cycles web article, based on my gemini interaction using GeneBellinger's AI prompts
Food intelligence book summary
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