Insight diagram

Part of Urea Kinetic model for Clearance Experiments

Clone of Clone of Dialysis blood flow
Insight diagram

Periodic table of disease patterns and physiological circuits   from Ch 9 of Uri Alon's System Medicine Book Circuit motifs are modified to facilitate building system dynamics simulations

System Medicine Physiological Circuits Disease Patterns
Insight diagram

Hannon and Ruth Modeling Dynamic Biological Systems p67 adapted to Bond Graph Kinetic Modeling Metabolic Map Alternate Layout of insight IM-857 Here Join and Split Flows are unfolded rather than using folders around the Stocks.

Clone of Catalyzed Reaction (Michaelis Menten) 2 with split and join
Insight diagram

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker


Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

Clone of Clone of Glucose-Insulin Model in Type 1 Diabetes
Insight diagram
WIP From  zenker 2007 article PLoS Computational Biology From Inverse Problems in Mathematical Physiology to Quantitative Differential Diagnoses
Clone of Cardiovascular Model
Insight diagram
Modelo de proceso de la glucosa
Insight diagram

Part of Urea Kinetic model for Clearance Experiments

Clone of Dialysis blood flow
Insight diagram
WIP From  zenker 2007 article PLoS Computational Biology From Inverse Problems in Mathematical Physiology to Quantitative Differential Diagnoses
Clone of Cardiovascular Model
Insight diagram
WIP Book Summary 
Janeways Immunobiology 9th Edition
Insight diagram

Addition of glucagon hormone action to control glucose homeostasis extended from IM-586

Clone of Glucose regulation CLD 2
Insight diagram

Part of Urea Kinetic model for Clearance Experiments

Clone of Dialysis blood flow
Insight diagram

From Tarek KA Hamid's Book Thinking in Circles About Obesity Springer 2009

Clone of Obesity Thinking in Circles
Insight diagram

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker


Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

Clone of Clone of Glucose-Insulin Model in Type 1 Diabetes
Insight diagram
Stock flow map of Immune System Cell type proliferation and differentiation, migration and circulation from Figs 1.3, 8.14 and 8.33 from Janeway's Immunobiology see Insight . Does not include cell death, interactions or inhibitory and promoting factors
Immune System Development
Insight diagram

Additional of glucagon hormone action to control glucose homeostasis

Clone of Glucose regulation CLD 2
Insight diagram

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker


Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

Clone of Clone of Glucose-Insulin Model in Type 1 Diabetes
Insight diagram

WIP Physiological circuits insight integrated with other articles on inflammation fibrosis and innate immunity

Multiscale integration of Inflammation and fibrosis
Insight diagram

Hannon and Ruth Modeling Dynamic Biological Systems p67 adapted to Bond Graph Kinetic Modeling Metabolic Map Alternate Layout of insight IM-857 Here Join and Split Flows are unfolded rather than using folders around the Stocks.

Clone of Catalyzed Reaction (Michaelis Menten) 2 with split and join
Insight diagram

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Clone of Glucose minimal model
Insight diagram

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Glucose minimal model Cambio#1
Insight diagram
Clone of Clone of Glucose-Insulin Model in Type 1 Diabetes
Insight diagram
Theories and models of heredity from Rethinking heredity, again R. Bonduriansky 2012 article
Heredity Theories and Models
Insight diagram

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Clone of Glucose minimal model
Insight diagram

WIP Physiological circuits insight integrated after other articles on inflammation fibrosis and innate immunity pictures insight 

Multiscale integration of Inflammation and fibrosis 2