This three loop goal-seeking structure identifies the three key influences on managing blood glucose for people with diabetes - insulin injections reduce blood glucose levels, exercise reduces blood glucose levels, and food increases blood glucose levels. The balance of all three is necessary to manage diabetes.
Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker
Glucose Insulin Model Info:
Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.
Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.
Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker
Glucose Insulin Model Info:
Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.
Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker
Glucose Insulin Model Info:
Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.
Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker
Glucose Insulin Model Info:
Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.
Simple goal seeking loop for type 1 diabetes, describing relationship between blood glucose level, insulin injections, and food consumption, seeking to achieve healthy balanced blood glucose levels in the body.
Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker
Glucose Insulin Model Info:
Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.
A simple glucose regulation causal loop diagram taken from Richard O. Foster, 1970: The Dynamics of blood sugar regulation, MSc thesis, MIT Dept of Electrical Engineering, available on the MIT System Dynamics Group Literature Collection and in the MIT Electronic Libraries. See IM-587 for Addition of Glucagon