From Tarek KA Hamid's Book Thinking in Circles About Obesity Springer 2009

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker

Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

Theories and models of heredity from Rethinking heredity, again R. Bonduriansky 2012 article

Part of Urea Kinetic model for Clearance Experiments

Addition of glucagon hormone action to control glucose homeostasis extended from IM-586

WIP Book Summary 

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker

Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

Working model of Erythropoiesis and Erythropoiesis Stimulating Agents (ESA) Dosing in Anemia due to Renal Failure from Jim Rogers See Stock Flow Map  Insight 810  and Simpler Dosing Model at IM-26182

Part of Urea Kinetic model for Clearance Experiments

Mammary gland structures example from Progress in Biophysics & Molecular Biology Special Issue 2016 From the century of the genome to the century of the organism: Montevil paper on organogenesis. Compare with Bogdanov (click tag)

Additional of glucagon hormone action to control glucose homeostasis

Hannon and Ruth Modeling Dynamic Biological Systems p67 adapted to Bond Graph Kinetic Modeling Metabolic Map Alternate Layout of insight IM-857 Here Join and Split Flows are unfolded rather than using folders around the Stocks.

Examples of macroanalysis relevant to representing causal mechanisms linking genes to diseases from darden2018 MecCog article and 2017 Product to Process article

Stock flow map of Immune System Cell type proliferation and differentiation, migration and circulation from Figs 1.3, 8.14 and 8.33 from Janeway's Immunobiology see Insight . Does not include cell death, interactions or inhibitory and promoting factors

Summary of Gizem Aktas M Sc thesis and prize winning paper from ISDC2018 extended abstract pdf 

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

WIP Physiological circuits insight integrated after other articles on inflammation fibrosis and innate immunity pictures insight 

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Part of Urea Kinetic model for Clearance Experiments

From Andrea De Gaetano et al (2012)  paper

Minimal model of glucose kinetics by Bergman, used to calculate insulin sensitivity from an Intravenous Glucose Tolerance Test (IVGTT). Plasma insulin I(t) enters a remote compartment X(t) where it is active in accelerating glucose G(t) disappearance into the periphery and liver, and inhibiting hepatic glucose production. Adapted from Minimal Models for Glucose and Insulin Kinetics: A Matlab implementation by Natal van Riel, Eindhoven University of Technology 2004 by Mark Heffernan.

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.