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Wenn kein Versuch unternommen wird, SARS-CoV-2 auszurotten, wird es schließlich endemisch und unausrottbar werden, mit hohen, nicht endenden Kosten für die Welt in Bezug auf Wirtschaftswachstum, menschliche Gesundheit und Menschenleben. Die derzeitige Strategie der meisten Regierungen besteht darin, restriktive Maßnahmen zu ergreifen, wenn das Virus die Krankenhäuser zu überschwemmen droht und diese Beschränkungen wieder zu lockern, wenn diese Gefahr zurückgeht. Diese Strategie kann die hochinfektiöse Delta-Variante, die einen geschätzten R0-Wert von 6 bis 9 hat, nicht eliminieren. Regelmäßige Sperrungen werden sich in Zukunft kaum vermeiden lassen.

Eine Ausrottung ist jedoch möglich, ebenso wie eine weltweit schnell erreichte Herdenimmunität, die den R0-Wert dauerhaft auf unter 1 senkt und somit zum Verschwinden des Virus führen wird. Entscheidend dafür ist Ivermectin, ein Medikament, das billig und leicht verfügbar ist und in den meisten Ländern hergestellt werden kann. Eine kürzlich durchgeführte Metastudie hat gezeigt, dass die prophylaktische Anwendung von Ivermectin eine Infektion mit dem Virus im Durchschnitt um 86 % verhindern kann, was der Wirksamkeit von Impfstoffen sehr ähnlich ist. Die, die nicht geimpft wurden und nicht immun sind, weil sie Covid-19 überstanden haben, könnten sich mit Ivermectin sehr effektiv vor einer Infektion schützen.  Die Ausrottung erfordert den Einsatz aller in der Grafik gezeigten Instrumente: künftige Generationen könnte es erspart bleiben mit dieser Plage leben zu müssen.  

SarsCov 2: die Unterbrechung seiner Dynamik
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Modelling the demand for health and care resources resulting from the Covid-19 outbreak using an SEIR model.

Clone of Infectious Disease Model (Version 4.0)
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Индия короновирус, 2021 жыл
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Modelling the demand for health and care resources resulting from the Covid-19 outbreak using an SEIR model.

Clone of Infectious Disease Model V1.0
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Modelling the demand for health and care resources resulting from the Covid-19 outbreak using an SEIR model.

Clone of Clone of Infectious Disease Model (Version 4.0)
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COVID-19 Systems Model
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Spring, 2020: in the midst of on-line courses, due to the pandemic of Covid-19.

With the onset of the Covid-19 coronavirus crisis, we focus on SIRD models, which might realistically model the course of the disease.

We start with an SIR model, such as that featured in the MAA model featured in
https://www.maa.org/press/periodicals/loci/joma/the-sir-model-for-spread-of-disease-the-differential-equation-model

Without mortality, with time measured in days, with infection rate 1/2, recovery rate 1/3, and initial infectious population I_0=1.27x10-4, we reproduce their figure

With a death rate of .005 (one two-hundredth of the infected per day), an infectivity rate of 0.5, and a recovery rate of .145 or so (takes about a week to recover), we get some pretty significant losses -- about 3.2% of the total population.

Resources:
  1. http://www.nku.edu/~longa/classes/2020spring/mat375/mathematica/SIRModel-MAA.nb
  2. https://www.maa.org/press/periodicals/loci/joma/the-sir-model-for-spread-of-disease-the-differential-equation-model
Clone of Coronavirus: A Simple SIR (Susceptible, Infected, Recovered) with death
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Collapse of the economy, not just recession, is now very likely. To give just one possible cause, in the U.S. the fracking industry is in deep trouble. It is not only that most fracking companies have never achieved a free cash flow (made a profit) since the fracking boom started in 2008, but that  an already very weak  and unprofitable oil industry cannot cope with extremely low oil prices. The result will be the imminent collapse of the industry. However, when the fracking industry collapses in the US, so will the American economy – and by extension, probably, the rest of the world economy. To grasp a second and far more serious threat it is vital to understand the phenomenon of ‘Global Dimming’. Industrial activity not only produces greenhouse gases, but emits also sulphur dioxide which converts to reflective sulphate aerosols in the atmosphere. Sulphate aerosols act like little mirrors that reflect sunlight back into space, cooling the atmosphere. But when economic activity stops, these aerosols (unlike carbon dioxide) drop out of the atmosphere, adding perhaps as much as 1° C to global average temperatures. This can happen in a very short period time, and when it does mankind will be bereft of any means to mitigate the furious onslaught of an out-of-control and merciless climate. The data and the unrelenting dynamic of the viral pandemic paint bleak picture.  As events unfold in the next few months,  we may discover that it is too late to act,  that our reign on this planet has, indeed,  come to an abrupt end?  
Clone of Covid 19 - irreversible and catastrophic consequences
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Modelo epidemiológico simples
SIR: Susceptíveis - Infectados - Recuperados

Dados iniciais do Brasil em 04 Abr 2020
Fonte:
https://www.worldometers.info/coronavirus/country/brazil/
Clone of Modelo SIR simples - Covid-19
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Here we have a basic SEIR model and we will investigate what changes would be appropriate for modelling the 2019 Coronavirus 

Modelo SEIR para COVID-19
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This System Model presents the cases of COVID-19 in Puerto Princesa City as of June 3, 2021

Insight Author: Pia Mae M. Palay
Clone of System Dynamic Model of COVID 19 in Puerto Princesa City
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The System Dynamics Model presents the the COVID-19 status in Puerto Princesa City
Clone of Clone of Ph_Covid19SDM_AngelKateCacayan
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Model ini dirancang untuk membuat model tentang penyebaran Covid-19 dan vaksinasi di Kabupaten Sleman pada November 2022

Model ini dibuat untuk memenuhi tugas kelompok dari matakuliah Metode Penyelesaian Masalah dan Pemodelan, atas nama :
Sabilla Halimatus Mahmud
Nurul Widyastuti
Muhammad Najib



SNM Model Penyebaran Covid-19 di Kabupaten Sleman
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COVID-19 outbreak in Burnie Tasmania Simulation Model

Introduction

This model simulates how COVID-19 outbreak in Burnie and how the government responses influence the economic community.  Government responses are based on the reported COVID-19 cases amount, whcih is considered to be based on testing rate times number of people who are infected minus those recovered from COVID-19 and dead.
Government interventions include the implement of healthy policy, border surveillance, quarantine and travel restriction. After outbreak, economic activities are positively affected by the ecommerce channel development and normal economic grwoth, while the unemployement rate unfortunately increases as well. 

Assumption
  • Enforcing government policies reduce both infection and economica growth.                                                                                                         
  • When there are 10 or greater COVID-19 cases reported, the governmwnt policies are triggered.                                                          
  • Greater COVID-19 cases have negatively influenced the economic activities.                                                                                             
  • Government policies restict people's activities socially and economically, leading to negative effects on economy.                                          
  • Opportunities for jobs are cut down too, making umemployment rate increased.                                                                                   
  • During the outbreak period, ecommerce has increased accordingly because people are restricted from going out.                                  
Interesting insights

An increase in vaccination rate will make difference on reduing the infection. People who get vaccinated are seen to have higher immunity index to fight with COVID-19. Further research is needed.

Testing rate is considered as critical issue to reflect the necessity of government intervention. Higher testing rate seems to boost immediate intervention. Reinforced policies can then reduce the spread of coronvirus but absoluately have negative impacts on economy too.
Clone of Mengling Xue 561743 BMA708_Marketing insights into Big Data
Insight diagram
Modelling the demand for health and care resources resulting from the Covid-19 outbreak using an SEIR model.

Clone of Infectious Disease Model (Version 3.0)
Insight diagram
Collapse of the economy, not just recession, is now very likely. To give just one possible cause, in the U.S. the fracking industry is in deep trouble. It is not only that most fracking companies have never achieved a free cash flow (made a profit) since the fracking boom started in 2008, but that  an already very weak  and unprofitable oil industry cannot cope with extremely low oil prices. The result will be the imminent collapse of the industry. However, when the fracking industry collapses in the US, so will the American economy – and by extension, probably, the rest of the world economy. To grasp a second and far more serious threat it is vital to understand the phenomenon of ‘Global Dimming’. Industrial activity not only produces greenhouse gases, but emits also sulphur dioxide which converts to reflective sulphate aerosols in the atmosphere. Sulphate aerosols act like little mirrors that reflect sunlight back into space, cooling the atmosphere. But when economic activity stops, these aerosols (unlike carbon dioxide) drop out of the atmosphere, adding perhaps as much as 1° C to global average temperatures. This can happen in a very short period time, and when it does mankind will be bereft of any means to mitigate the furious onslaught of an out-of-control and merciless climate. The data and the unrelenting dynamic of the viral pandemic paint bleak picture.  As events unfold in the next few months,  we may discover that it is too late to act,  that our reign on this planet has, indeed,  come to an abrupt end?  
Clone of Covid 19 - irreversible and catastrophic consequences
Insight diagram
SARS-CoV-19 spread in different countries
- please adjust variables accordingly

Italy
  • elderly population (>65): 0.228
  • estimated undetected cases factor: 4-11
  • starting population size: 60 000 000
  • high blood pressure: 0.32 (gbe-bund)
  • heart disease: 0.04 (statista)
  • free intensive care units: 3 100

Germany
  • elderly population (>65): 0.195 (bpb)
  • estimated undetected cases factor: 2-3 (deutschlandfunk)
  • starting population size: 83 000 000
  • high blood pressure: 0.26 (gbe-bund)
  • heart disease: 0.2-0.28 (herzstiftung)
  • free intensive care units: 5 880

France
  • elderly population (>65): 0.183 (statista)
  • estimated undetected cases factor: 3-5
  • starting population size: 67 000 000
  • high blood pressure: 0.3 (fondation-recherche-cardio-vasculaire)
  • heart disease: 0.1-0.2 (oecd)
  • free intensive care units: 3 000

As you wish
  • numbers of encounters/day: 1 = quarantine, 2-3 = practicing social distancing, 4-6 = heavy social life, 7-9 = not caring at all // default 2
  • practicing preventive measures (ie. washing hands regularly, not touching your face etc.): 0.1 (nobody does anything) - 1 (very strictly) // default 0.8
  • government elucidation: 0.1 (very bad) - 1 (highly transparent and educating) // default 0.9
  • Immunity rate (due to lacking data): 0 (you can't get immune) - 1 (once you had it you'll never get it again) // default 0.4

Key
  • Healthy: People are not infected with SARS-CoV-19 but could still get it
  • Infected: People have been infected and developed the disease COVID-19
  • Recovered: People just have recovered from COVID-19 and can't get it again in this stage
  • Dead: People died because of COVID-19
  • Immune: People got immune and can't get the disease again
  • Critical recovery percentage: Chance of survival with no special medical treatment
Clone of SARS-CoV-19 model
Insight diagram

This Model was first developed from the SIR model (Susceptible, Infected, Recovered). It was designed to explore relationship between the government policies regarding the COVID-19 and its influences on the economy as well as well-being of local residents. 

 

Assumptions:

Government policies will be triggered when reported COVID-19 case are 10 or less;

Government policies reduces the infection and economic growth at the same time.

 


Interesting Insights:

In the first two weeks, the infected people showed an exponential growth, in another word, that’s the most important period to control the number of people who got affected. 

 

Clone of Model of COVID-19 Outbreak in Burnie, Tasmania
Insight diagram

This Model was first developed from the SIR model (Susceptible, Infected, Recovered). It was designed to explore relationship between the government policies regarding the COVID-19 and its influences on the economy as well as well-being of local residents. 

 

Assumptions:

Government policies will be triggered when reported COVID-19 case are 10 or less;


Government policies reduces the infection and economic growth at the same time;


Ro= 5.7  Ro is the reproduction number, here it means one person with COVID-19 can potentially transmit the coronavirus to 5 to 6 people,

 


Interesting Insights:

In the first two weeks, the infected people showed an exponential growth, in another word, that’s the most important period to control the number of people who got affected. 

 

Clone of Model of COVID-19 Outbreak in Burnie, Tasmania
Insight diagram
Modelo epidemiológico simples
SIR: Susceptíveis - Infectados - Recuperados

Clique aqui para ver um vídeo com a apresentação sobre a construção e uso deste modelo.  É recomendável ver o vídeo num computador de mesa para se poder ver os detalhes do modelo.


Dados iniciais de infectados, recuperados e óbitos para diversos países (incluindo o Brasil) podem ser obtidos aqui neste site.
Clone of Modelo SIR simples - Covid 19
Insight diagram

This Model was first developed from the SIR model (Susceptible, Infected, Recovered). It was designed to explore relationship between the government policies regarding the COVID-19 and its influences on the economy as well as well-being of local residents. 

 

Assumptions:

Government policies will be triggered when reported COVID-19 case are 10 or less;

Government policies reduces the infection and economic growth at the same time.

 


Interesting Insights:

In the first two weeks, the infected people showed an exponential growth, in another word, that’s the most important period to control the number of people who got affected. 

 

Clone of Clone of Model of COVID-19 Outbreak in Burnie, Tasmania
Insight diagram
A sample model for class discussion modeling COVID-19 outbreaks and responses from government with the effect on the local economy.  Govt policy is dependent on reported COVID-19 cases, which in turn depend on testing rates less those who recover

Assumptions
Govt policy reduces infection and economic growth in the same way.

Govt policy is trigger when reported COVID-19 case are 10 or less.

A greater number of COVID-19 cases has a negative effect on the economy.  This is due to economic signalling that all is not well.

Interesting insights

Higher testing rates seem to trigger more rapid government intervention, which reduces infectious cases.  The impact on the economy though of higher detected cases though is negative. 




Clone of Burnie COVID-19 outbreak demo model version 2
Insight diagram
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[Explore The Model]
کلیک کنید

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Clone of شگفتی سازهای تاثیر گذار بر محورمقاومت در جهان پساکرونا
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The System Dynamics Model presents the the COVID-19 status in Puerto Princesa City
Clone of Clone of Ph_Covid19SDM_AngelKateCacayan